Oxbryta Lawsuit in Boston

Oxbryta Lawsuit in Boston: Holding Pfizer Accountable

Oxbryta was developed to treat anemia in individuals with Sickle Cell Disease (SCD). Its goal was to increase hemoglobin levels and reduce the impact of sickled red blood cells. However, in September 2024, the drug was recalled from both U.S. and international markets after post-clinical trial data raised alarming concerns.

These studies linked Oxbryta to severe health risks, including a higher chance of vaso-occlusive crises (VOC), organ damage, and even fatal outcomes.

If you or a loved one took Oxbryta (Voxelotor) and suffered serious health complications, you may be eligible to file an Oxbryta lawsuit in Boston. At Rueb Stoller Daniel, we are committed to holding Pfizer Inc. accountable for its negligence. Contact our Boston mass tort and class action lawyers today for a free consultation.

About Oxbryta (Voxelotor)

Oxbryta, known by its generic name Voxelotor, was developed to treat sickle cell disease. It was created by Global Blood Therapeutics and received FDA approval in 2019.

In 2022, Pfizer acquired Global Blood Therapeutics. Due to reports of severe side effects and fatal complications, Pfizer recalled Oxbryta from the market on September 25, 2024.

The Oxbryta Recall

Pfizer voluntarily recalled Oxbryta on September 25, 2024, due to serious health risks discovered in post-clinical trials. The drug, originally developed to treat anemia in patients with Sickle Cell Disease (SCD), was found to increase the risk of vaso-occlusive crises (VOCs), organ damage, and death. These findings showed that the dangers of taking Oxbryta outweighed its potential benefits for sickle cell patients.

The decision to recall Oxbryta came after alarming results from studies. In the Hope Kids 2 trial with 236 children, eight deaths occurred among patients taking Oxbryta compared to only two in the placebo group. Additionally, the RESOLVE study examining sickle cell disease patients with leg ulcers reported eight deaths among participants.

These concerning outcomes, along with the increased frequency of painful VOCs, led Pfizer to withdraw Oxbryta from all global markets to protect patient safety. We’ve created a blog examining Oxbryta’s global recall and what it means for patients in detail.

If you’re in Boston and believe you’ve been affected by this recalled medication, reach out to us to learn about your legal options.

sickle cell disease, normal and sickle red blood cells

Oxbryta Was Meant to Treat Sickle Cell Disease

Sickle cell disease (SCD) is a genetic blood disorder that alters the shape of red blood cells, causing them to become crescent or sickle-shaped. These rigid, sticky cells can obstruct blood flow, leading to severe health complications.

Serious complications of SCD include:

  • Infections due to a weakened immune system.
  • Acute Chest Syndrome: Sickled cells block oxygen flow to the lungs, causing a medical emergency.
  • Stroke: The irregular cells increase the risk of clotting.
  • Organ failure: Chronic blood flow restriction damages organs.
  • Vaso-occlusive crises (VOCs): Extremely painful episodes are triggered by blocked blood vessels.
  • Hemolytic anemia: The body lacks enough healthy red blood cells, leading to fatigue and shortness of breath.

Traditional sickle cell treatments have centered around symptom management, including blood transfusions and pain relief medications. Oxbryta, developed by Global Blood Therapeutics (GBT), was intended to address the root problem—faulty hemoglobin.

Hemoglobin is the protein in red blood cells that carries oxygen. In sickle cell disease patients, defective hemoglobin leads to the misshaping of red blood cells. Oxbryta was designed to help hemoglobin bind more efficiently to oxygen.

Oxbryta Side Effects and Serious Complications

The most frequently reported side effects of Oxbryta include nausea, diarrhea, and headaches. Some users have also experienced severe allergic reactions.

The drug was recalled due to reports of serious health risks and complications. Lawsuits claim that Global Blood Therapeutics (GBT) and Pfizer didn’t adequately inform sickle cell patients of the dangers.

Vaso-Occlusive Crises (VOC)

Some individuals taking Oxbryta have reported an increased occurrence of vaso-occlusive crises (VOCs), also referred to as sickle cell crises. These crises occur when sickled red blood cells obstruct blood flow in small vessels, depriving organs and tissues of oxygen. This can result in severe pain and lasting damage.

Common symptoms of vaso-occlusive crises include intense pain in the abdomen, joints, bones, or lungs. These painful episodes may persist for several hours to days. If they recur frequently, VOCs can lead to life-threatening complications.

Sickle cell crises may result in:

  • Acute chest syndrome
  • Stroke
  • Organ failure, including kidney failure
  • Pulmonary embolism

Severe Health Risks and Fatalities

Oxbryta has been associated with serious complications, including fatal outcomes. Clinical trials conducted after the drug’s release indicated a higher mortality rate among patients taking Oxbryta compared to those in the placebo group.

The medication may heighten the risk of:

  • Organ failure, such as kidney or liver failure
  • Stroke and heart attack

Anyone who has taken Oxbryta and suffered adverse effects should meticulously document their symptoms and medical history.

Who Qualifies for an Oxbryta Lawsuit in Boston?

If you or a loved one have experienced severe health complications after using Oxbryta, you may be eligible to file a lawsuit. At Rueb Stoller Daniel, we are dedicated to helping individuals who have suffered harm due to dangerous or defective drugs. To be eligible for an Oxbryta lawsuit, individuals must meet the following criteria:

  • Usage Requirements: You must have taken Oxbryta for at least 30 days.
  • Complications After Oxbryta Use:
    • Increased Vaso-Occlusive Crises (VOC)
    • Stroke
    • Heart Attack
    • Organ Failure (e.g., kidney or liver failure)
    • Death

If you experienced complications or lost a family member, our team can help you pursue justice and compensation. Contact Rueb Stoller Daniel today for a free case evaluation and to discuss your legal options.

Who can file an Oxbryta lawsuit in Boston?

Damages in an Oxbryta Lawsuit

Individuals who have suffered harm from Oxbryta may pursue legal action to obtain compensation for the medical, financial, and emotional impact of the drug’s side effects. At Rueb Stoller Daniel, we advocate for victims and strive to recover maximum compensation on their behalf.

Medical Expenses

Plaintiffs may seek reimbursement for medical costs related to Oxbryta complications, such as:

  • Emergency treatment for severe reactions such as strokes or cardiac issues.
  • Hospital costs from complications like organ failure.
  • Costs for ongoing medical care, including dialysis and rehabilitation.
  • Prescription drugs to manage new health conditions from Oxbryta use.
  • Future healthcare costs for chronic conditions or disabilities caused by Oxbryta

Lost Wages and Diminished Earnings

Side effects from Oxbryta may prevent individuals from working temporarily or permanently. Compensation may be available for:

  • Lost wages due to hospitalization and recovery.
  • Reduced earning potential if you are disabled or cannot earn as much income

Additional Financial Costs

Plaintiffs may also claim monetary compensation for:

  • Travel and transportation expenses related to medical treatment.
  • Home alterations for accessibility, such as wheelchair ramps.
  • Professional caregiving services or financial losses by family members who provide care.

Pain and Suffering

These damages are more challenging to calculate. Pain and suffering compensation may include:

  • Physical suffering
  • Emotional and psychological distress, including PTSD, anxiety, and depression.
  • Diminished quality of life due to permanent injuries or disabilities.

Loss of Consortium

Spouses may receive compensation for the loss of companionship, emotional support, and intimacy due to their partner’s injuries.

Wrongful Death Claims

Families who have lost a loved one due to Oxbryta complications may pursue compensation for:

  • Funeral and burial expenses
  • Lost financial support from the deceased
  • Loss of companionship and emotional support

Punitive Damages

If the pharmaceutical company committed serious negligence or misconduct, courts may award additional money to victims. These punitive damages are intended to punish wrongdoing.

For personalized legal guidance, contact Rueb Stoller Daniel for a free case evaluation.

Boston Oxbryta lawyer

How to File an Oxbryta Lawsuit in Boston, MA

If you or a loved one has suffered complications from Oxbryta, you may be entitled to financial compensation. Navigating a lawsuit can feel overwhelming, but Rueb Stoller Daniel’s attorneys are ready to assist Boston residents every step of the way.

Collecting Evidence for Your Claim

A successful case relies on strong evidence, such as:

  • Medical Records – Proof of Oxbryta use and related health problems.
  • Doctor and Pharmacy Communications – Details about any warnings given.
  • Reports of Side Effects – Any complaints to the FDA or medical professionals.
  • Expert Testimony – Specialists who can explain Oxbryta’s risks.

It’s crucial to act fast to preserve valuable evidence for an Oxbryta lawsuit. Contact us today to start your claim.

Settlement or Trial?

Most defective drug lawsuits result in settlements. However, if your case goes to trial, our skilled trial lawyers will be by your side, fighting for the best possible outcome.

The Deadline for Oxbryta Lawsuits in Massachusetts

The statute of limitations for personal injury cases in Massachusetts is three years from the date of the injury or accident. That means you generally have three years to file an Oxbryta lawsuit after being harmed.

However, there are exceptions to the time limit. If your health problems weren’t immediately apparent, the “discovery rule” may apply. This means the two-year clock starts ticking from when you discovered or reasonably should have discovered your injury.

If you don’t file your case by the deadline, you could lose your right to seek compensation. It’s important to contact a Boston Oxbryta lawyer as soon as possible.

How Much Will Hiring an Oxbryta Attorney in Boston Cost?

At Rueb Stoller Daniel, we work on a contingency fee basis. This means you don’t pay anything upfront—we only receive payment if we successfully win your case. Your Boston Oxbryta lawyer earns a percentage of the final settlement or lawsuit payout.

Why Choose Rueb Stoller Daniel?

At Rueb Stoller Daniel, we’re here to help you navigate the legal process and fight for the maximum compensation. We give your case personalized attention, treating you like a person, not just a file number.

  • Experience: Gregory Rueb, Paul Stoller, and Stephen Daniel have over fifty years of combined experience. Our team has represented tens of thousands of clients across the country.
  • Results: We have recovered hundreds of millions of dollars for clients.
  • Reputation: Our law firm has earned a variety of awards and memberships.

Contact Us Today for a Free Case Review

At Rueb Stoller Daniel, we understand the challenges patients with sickle cell disease face and the risks associated with Oxbryta. If you or a loved one has suffered due to Oxbryta, don’t wait to take action. Contact us today to schedule your free consultation.

You can reach us by calling 1-866-CALL-RSD or filling out our online form. We are available 24/7.